An AI-driven, expert-reviewed CRO & CDMO. A curated AI engine proposes retrosynthesis routes, our knowledge base grounds them, and a PhD synthetic chemist verifies, scales and costs every one — then our lab synthesizes and delivers the compound, from mg to multi-kg. You get both the decision-ready report and the material.
Astinova Bio Labs is an AI-driven, expert-reviewed contract research and manufacturing organization — every route AI-designed and verified by PhD synthetic chemists — delivering pioneering chemistry across pharmaceutical intermediates, specialty chemicals, impurities and active pharmaceutical ingredients.
Founded by synthetic chemists with a vision to provide best-in-class pharmaceutical services, we pair a curated AI retrosynthesis engine with the judgment of a PhD synthetic chemist — so automation makes us fast, and expertise makes us right.
Specialty chemicals, organic materials and key intermediates.
Non-infringing route development and scheme optimization.
Active pharmaceutical ingredients and key starting materials.
mg to multi-kg deliveries under GMP-standard quality.
FFS Model
Synthesis of listed and non-listed products from mg to kg scale, with quality analysis and specification setting for every deliverable.
FTE Model
Challenging projects with little or no literature precedent. A dedicated scientist is assigned, with weekly progress reporting to the client.
One-time Basis
Literature search, route scouting and scheme optimization for cost-effective, eco-friendly non-infringing processes, ready for scale-up.
The engine proposes, our knowledge base grounds it, a PhD synthetic chemist verifies — then our lab synthesizes and delivers the molecule. You get the decision-ready report and the material, from one team. Automation makes us fast; expertise makes us right.
Curated retrosynthesis search proposes candidate routes for any target, known or novel.
Industrial templates, textbook and FDA-drug corpora anchor the chemistry.
A PhD synthetic chemist corrects, scales and costs every route before it ships.
A cited, hazard-aware, scale-matched deliverable you can fund, run and stand behind.
Our lab runs the route and ships the physical compound — mg to multi-kg, with CoA and full documentation.
“Sell the chemist, not the script.”
The platform scales our throughput — it never replaces the expert judgment our clients pay for.
Engage us for expert-reviewed synthesis intelligence, for physical compounds made in our labs, or both — from one team, in one IP context.
Lab, kilo and commercial routes for one target, each scale-matched with conditions, yield, cost and hazard.
Top-route portfolios for novel chemical entities, with scaffold / fragment analysis and synthetic-feasibility review.
Originator-patent-grounded routes for commercial APIs, with operational detail from the granted-patent examples.
Step-wise costed workbooks with route-vs-route economics and dominant-cost-driver analysis.
Current-vs-recommended optimization of a fixed route for cost, safety and yield.
Disconnection diversity and IP-landscape-aware design (informational; not a legal FTO opinion).
Bespoke synthesis of listed and non-listed compounds, mg to multi-kg, with quality analysis and specification setting per deliverable.
Active pharmaceutical ingredients, key starting materials and advanced intermediates, delivered to specification.
Verified routes carried through to gram-to-multi-kg batches under GMP-standard quality, with CoA and batch records.
Synthesized and characterized impurity, metabolite and isotope-labeled standards, made to order.
PROTAC, molecular-glue, ADC payload/linker and ionizable-lipid building blocks via convergent synthesis.
Custom building blocks and key starting materials from our catalog and by request — the chemistry behind the routes.
Route simplification by recognising a one-step core disconnection the engine alone missed.
Process-route redesign tripling end-to-end yield via a late-stage strategy change.
Three scale-matched routes delivered for a single molecule, discovery through manufacture.
Representative, anonymised results from delivered client and internal case studies. Figures reflect specific projects and are not guarantees.
Beyond services, we invest in first-in-class chemistry of our own — an internally funded discovery program advanced in-house.
CRBN ligand (pomalidomide-type)
Route design and expert-verified chemistry across the modalities driving modern drug discovery.
NCE route design, multi-scale routes and generic API routes.
Warhead–linker–E3 ligand assembly and degrader route design.
Linker-payload components and ionizable LNP lipids, with honest scale caps.
Multi-centre chiral building blocks and divergent disconnection maps.
Every deliverable passes a 6-point audit — structures, disconnections, conditions, quantitative claims, citations and protecting-group logic — before it ships.
Citations checked against Crossref / PubMed / USPTO; CAS confirmed on PubChem. Where conditions are uncertain, we leave them blank rather than wrong.
Client structures are covered by NDA, stored encrypted, never reused or used to train models. Your chemistry stays yours.
When the engine misses or a route is weak, we say so — and show the real chemistry. Credibility is the product.
Single target, fixed scope
Ongoing route pipeline
Self-service intake (coming)
Discovery medicinal chemistry and scalable process chemistry under one roof.
A curated AI stack you cannot buy off the shelf — engine, drug corpora and retrieval combined.
Founded and led by a PhD synthetic chemist with postdoctoral process-chemistry experience — every report carries that bench-and-plant judgment.
A discipline of checking every claim — the reason clients trust what we hand them.
NDA-backed, single-expert handling — built for sensitive early-stage chemistry.
Automation makes us fast. Expertise makes us right. That balance is the whole company.
Bring us a target — known or novel. We return scale-matched, costed, verified routes your team can act on.
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